Patient-rated dry eye scores at baseline, after 3 days (midpoint), and 7 days’ treatment with Thealoz Duo ® or Systane ®. The liquid gel drops come in easy to squeeze single dose vial, A drop can be applied as often as necessary throughout the day

To help reduce or eliminate these symptoms, Thealoz Duo works in several ways due to the active ingredients Trehalose (as in Thealoz) and Sodium Hyaluronic Acid (also known as Hyabak). It is also free from preservatives.Proportion of patients with conjunctival hyperemia at baseline and after 7 days’ treatment with Thealoz Duo ® or Systane ®. Sodium hyaluronate adds moisture by retaining water to hydrate and lubricate the surface of the eye Dry Eye means that your eyes may not be making enough tears, the tears you are making are of poor quality or evaporate faster than they should.

The efficacy analyses were performed on the intent-to-treat sample (those randomized patients who received at least one drop of study medication and who provided at least some data for the primary efficacy variable). The safety analysis was performed on the safety sample (those patients who received at least one drop of study medication).A global ocular staining score was determined from the Oxford 0–5 grading scheme that assesses global ocular staining in corneal area from fluorescein coloration and in temporal and nasal areas from lissamine green coloration in both eyes. Ocular staining was measured during visits at days 0, 7, 12, and 19. contains 30 single-use unit doses. Once the vial has been opened throw away, even if there is a small amount left, do not reuse. Once opened the microbial protection of the solution cannot be guaranteed. NOTE: Please ensure that you wash your hands before using any of these products to prevent possible infection of your eyes. Palpebral signs including meibomitis and other blepharitis, conjunctival discharge, chemosis, folliculo-papillary conjunctivitis, filamentary keratitis, and other relevant ocular signs were evaluated in each eye at days 0, 7, 12, and 19. Palpebral signs were evaluated on a four-point scale (0= none, 1= mild, 2= moderate, 3= severe). Thealoz® Duo dry eye drops are suitable for all dry eye sufferers looking for the latest drop. They contain a unique combination of ingredients (trehalose plus sodium hyaluronate) that deliver long-lasting symptom relief(1) and protection for the surface of the eye.

OSDI scores at baseline and during treatment at baseline and after 7 days’ treatment with Thealoz Duo ® or Systane ®. Thealoz Duo ® (Laboratoires Théa, Clermont Ferrand, France) is an artificial tear preparation containing two active ingredients: trehalose, a naturally occurring disaccharide of glucose that appears to function in an anhydrobiotic capacity in many organisms, and hyaluronate, a widely distributed anionic glycosaminoglycan polysaccharide with biological roles associated with its lubricative and water-retaining properties. Trehalose has been shown not only to stabilize both bilipid membranes and labile proteins against desiccation, but also to have a protective effect against desiccation and oxidative insult in the mammalian eye. 4 Hyaluronate is a component of many medicinal preparations including those used in cataract surgery, for the treatment of dry eye as well as many commercial skin preparations and antiaging creams. 5 It is also present in natural human tears. 6 Patients with moderate to severe OSDI scores were reduced by 60%, vs. 36% with hyaluronic acid, alone.

No meibomitis or other blepharitis, conjunctival discharge, folliculo-papillary conjunctivitis or filamentary keratitis was reported at baseline or during either treatment. KOOSTUMUS: Trehaloosia (3 %), natriumhyaluronaatti (0,15 %), natriumkloridi, trometamoli, kloorivetyhappo ja injektionesteisiin käytettävä vesi. Clinically proven to stabilize tear film, reduce inflammatory markers and restore normal osmotic balance.